The needs of adolescents and the South African local context has changed and even with improving efforts for HIV. Currently, youth and young people have the lowest rates of adherence and the highest rates of infection in South Africa and we are still not able to respond to the needs of youth sufficiently. This dissertation offers a multipronged and multi-perspective approach to study adherence in adolescents who were perinatally infected with HIV, while at the same time remaining sensitive to the local South-African social-cultural and political context. This dissertation will be invaluable to the knowledge base here in South Africa. Through the co-production and co-creation of new knowledge with adolescents this qualitative participatory research will rely on adolescents as the knowledge experts. The exchange of experiences within their networks, the dissemination of their stories in their chosen method and the collation of data in a research documentary will increase awareness within their communities and engage in conversation other youths. Additionally,this study will contribute to a broader evidence base on enabling environments to promote adherence issues of youth and young people who were perinatally infected with HIV. The overarching aim of this study is to contribute to the ‘Transform the world’ sustainable development goals of the United Nations, by exploring the psychosocial and behavioral risks, lived experiences of adherence for perinatally infected HIV positive adolescents, as situated in a broader African socio-cultural, political and economic context, and to develop policy recommendations for enabling environments based on the research evidence collected.
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